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Articles
  • OpenAccess
  • An fMRI Study of Words Processing in Chinese Language  [CLMCR 2016]
  • DOI: 10.4236/jbm.2016.43002   PP.9 - 14
  • Author(s)
  • Pei Xu, Bing Sun, Chunqi Chang, Nan Hu
  • ABSTRACT
  • Using the blood oxygen levels dependent technology of magnetic resonance imaging (BLOD-fMRI), we aimed to explore the brain activation after visual stimulation by Chinese words. In the current study, 24 healthy volunteers (12 males, 12 females, right-handed, mean age 26 ± 2 years) were prospectively included. The event related design was used in the current fMRI study when participants silently read all words appearing in the middle of the screen. Images were processed with Statistical Parametric Mapping 8 (SPM8) software, by using a general linear model (GLM). Group activations were extracted from the 2nd level group analysis with a threshold of p < 0.001, and it was shown that the main activated areas by silent reading tasks were regions involved in brain semantic processing, including middle temporal gyrus, fusiform gyrus, supplementary motor area, inferior frontal gyrus, cingulate gyrus, superior parietal lobule and inferior parietal lobule. It was also learnt that superior parietal lobule and middle temporal gyrus are related with semantic understanding, lenticular nucleus are related with semantic processing. This means, in addition to the cerebral cortex, subcortical nuclei is also very important to the processing of words in Chinese language.

  • KEYWORDS
  • Functional Magnetic Resonance Imaging (fMRI), Brain Functional Area, Brain Activation
  • References
  • [1]
    Liu, C. (2013) Susceptibility-Weighted Imaging Using in Brain Tumor. Chinese Journal of Medical Imaging, 23, 265-272.
    [2]
    Yang, G., Zhang, Q., Zhang, Y., Shen, J., Zhang, X. and Chen, Q. (2009) An FMRI Study for Different Cognition Components of Working Memory in Schizophrenia Patients. Journal of China Medical Imaging, 20, 758-761.
    [3]
    Kemmerer, D., Rudrauf, D., Manzel, K. and Tranel, D. (2012) Behavioral Patterns and Lesion Sites Associated with Impaired Processing of Lexical and Conceptual Knowledge of Actions. Cortex, 48, 826-848.
    http://dx.doi.org/10.1016/j.cortex.2010.11.001
    [4]
    Vigliocco, G., Vinson, D.P., Druks, J., Barber, H. and Cappa, S.F. (2011) Nouns and Verbs in the Brain: A Review of Behavioural, Electrophysiological, Neuropsychological and Imaging Studies. Neuroscience and Biobehavioral, 35, 407-426.
    http://dx.doi.org/10.1016/j.neubiorev.2010.04.007
    [5]
    Zhang, L. Jin, Z., Li, K. and Liu, G. (2013) Cerebral Activations during Verb Generating and Picture Naming: A Study Using Functional MR Imaging. Radiol Practice, 28, 251-255.
    [6]
    Ping, L., Zhen, J. and Li, H. (2004) Neural Representations of Nouns and Verbs in Chinese: An fMRI Study. NeuroImage, 21, 1533-1541.
    http://dx.doi.org/10.1016/j.neuroimage.2003.10.044
    [7]
    Moseley, R.L. and Pulvermüller, F. (2014) Nouns, Verbs, Objects, Actions, and Abstractions: Local FMRI Activity Indexes Semantics, Not Lexical Categories. Brain and Language, 132, 28-42.
    http://dx.doi.org/10.1016/j.bandl.2014.03.001
    [8]
    Wang, J. (2011) The Asymptotic Theory of Generalized Linear Models. M.A. Thesis, Guangxi University, Guangxi.
    [9]
    Zhuang, Y., Shen, J., Xu, J., Zhou, Y. and Lu, Q. (2007) BOLD-FMRI on Aphasia in Patients with Ischemic Stroke: A Pilot Study. Chinese Journal of Medical Imaging, 17, 1143-1145.
    [10]
    Zhang, H., Yan, Z. and Lin, B. (2013) Study of Visual Cortex of Children Amblyopia with Blood Oxygen Level Dependent-Functional Magnetic Resonance Imaging. International Eye Science, 13, 918-920.
    [11]
    Ma, L., Tang, Y., Wang, Y., et al. (2002) Mapping Cortical Areas Associated with Chinese Word Processing with Functional Magnetic Resonance Imaging. Chinese Journal of Radology, 36, 198-201.
    [12]
    Chen, S., Zhang, Y., Zhang, X. and Xiao, Z. (2007) Specific Neural Basis of Chinese Idioms Processing: An Event- Related Functional MRI Study. Chinese Journal of Radology, 41, 930-933.
    [13]
    Tan, L., et al. (2003) Neural Systems of Second Languages Reading Are Shaped by Native Language. Human Brain Mapping, 18, 158-166.
    http://dx.doi.org/10.1002/hbm.10089
    [14]
    Jiang, M. (2011) FMRI Variability and the Localization of Languages in the Xinjiang Uygurs Brain. Ph.D. Thisis, Xinjiang Medical University, Xinjiang.
    [15]
    Pulvermüller, F., Lutzenberger, W. and Preissl, H. (1999) Nouns and Verbs in the Intact Brain: Evidence from Event- Related Potentials and High-Frequency Cortial Responses. Cerebral Cortex, 9, 497-506.
    http://dx.doi.org/10.1093/cercor/9.5.497

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