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Articles
  • OpenAccess
  • Mechanism of Magnetic Pulse Wave Signal for Blood Pressure Measurement  [iCBBE 2016]
  • DOI: 10.4236/jbise.2016.910B004   PP.29 - 36
  • Author(s)
  • Yang Zhang, Yibin Li, Xiaomeng Chen, Ning Deng
  • ABSTRACT
  • Continuous non-invasive blood pressure (BP) measurement can be realized by using pulse transit time (PTT) based on electrocardiogram (ECG) and pulse wave signal. Modulated magnetic signature of blood (MMSB) is a promising approach to obtain PTT. The origin of MMSB is critical to establish the relationship between MMSB and BP. In this paper, two possible origins of MMSB, blood disturbance mechanism and angular variation mechanism, are analyzed and verified through three control experi-ments under different conditions. The influence of blood velocity alteration and blood volume alteration on magnetic field is investigated though blood flow simulation sys-tem. It is found that MMSB comes mainly from the periodic blood flow while the per-turbation caused by angular variation between sensitive axis of the magnetic sensor and geomagnetic field can be neglected. As to blood disturbance mechanism, the change of blood volume plays a decisive role while the effect of blood velocity altera-tion is negligible.
  • KEYWORDS
  • Blood Pressure (BP), Modulated Magnetic Signature of Blood (MMSB), Pulse Transit Time (PTT)
  • References
  • [1]
    [1] Phua, C.T. and Lissorgues, G. (2009) Measurement of Blood Pressure Using Magnetic Me-thod of Blood Pulse Acquisition. Proceedings of the 2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, Taiwan, October 2009, 112-115.
    http://dx.doi.org/10.1109/NANOMED.2009.5559106
    [2]
    Joseph, J. and Jayashankar, V. (2010) Magnetic Sensor for Non-Invasive Detection of Blood Pulse and Estimation of Arterial Compliance. IEEE EMBS Conference on Biomedical Engineering & Sciences, Kuala Lumpur, Malaysia, 30 December 2010, 170-175.
    http://dx.doi.org/10.1109/iecbes.2010.5742222
    [3]
    Phua, C.T., Lissorgues, G. and Mercier, B. (2008) Non-Invasive Acquisition of Blood Pulse using Magnetic Disturbance Technique. Proceedings of 23rd International Conference of Biomedical Engineering, 786-789.
    [4]
    Joseph, J., Venkataraman, J. and Jagadeesh, V.K. (2011) Non-Invasive Esti-mation of Arterial Compliance. IEEE International Instrumentation & Measurement Tech-nology Conference, 480-484.
    [5]
    Li, Y.B., Gao, Y.Y. and Deng, N. (2013) Mechanism of Cuff-Less Blood Pressure Measurement Using MMSB. The 7th International Conference on Bioinformatics and Biomedical Engineering, 123-125.
    [6]
    Sinatra, F.L. (2010) Under-standing the Interaction between Blood Flow and an Applied Magnetic Field. University of South Florida.

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